botox in the bladder
Botulinum toxin (botox) injection into the bladder is a well-established treatment for overactive bladder and urgency incontinence, including urgency incontinence associated with neurological disease. The toxin relaxes the smooth muscle of the bladder wall, decreasing the frequency of contractions and temporarily increasing the capacity of the bladder. It may be used in adults with refractory symptoms who have failed to respond to adequate trials of anticholinergic medications.